This publication deals with the problems on the development of new medicine and herbal formulations from natural products and traditional drugs, technology transfer in bulk drugs manufacture through horizontal or vertical mechanism preferably through joint venture between the companies in the developing world, quality management, R&D on tropical diseases, bio-evaluation of drug molecules (in vitro and in vivo), provision and implications of TRIPS for drugs, manufacturing facilities and standards and modern methods of screening of natural products for developing new bioactives. Status of the development of drugs and pharmaceutical in some of the developing countries, viz., Bangladesh, Egypt, India, Iraq, Indonesia, Malaysia, Mauritius, Nepal, Syria and Zambia is also included in the publication.'